Kyle J. Eastman - Concepedia

Author

Kyle J. Eastman

Bristol-Myers Squibb (United States)ORCID

Also Known As

Eastman, K.J., Kyle Eastman, Kyle J Eastman, Kyle J. Eastman

Publications

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Pennsylvania State University Scripps Research Institute Yale University

About

Kyle J. Eastman is an author at Bristol-Myers Squibb (United States) specializing in medicine, drug discovery, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	92
2	Natural Sciences	2	2	42
3	Biochemistry	2	2	42
4	Engineering	1	1	63
5	Biomolecular Engineering	1	1	63

Kyle J. Eastman

Publications

539

Citations

H-Index

Page 1

	Year	Citations
Scalable Total Syntheses of <i>N</i>-Linked Tryptamine Dimers by Direct Indole−Aniline Coupling: Psychotrimine and Kapakahines B and F Timothy R. Newhouse, Chad A. Lewis, Kyle J. Eastman, Journal of the American Chemical Society	2010	180
A simple method for the direct arylation of indoles Kyle J. Eastman, Phil S. Baran Tetrahedron EngineeringOrganic ChemistryNatural Product SynthesisDirect ArylationSynthetic Chemistry	2008	63
Studies on the Mechanism of Action of Prekinamycin, a Member of the Diazoparaquinone Family of Natural Products: Evidence for Both sp<sup>2</sup> Radical and Orthoquinonemethide Intermediates Ken S. Feldman, Kyle J. Eastman Journal of the American Chemical Society	2006	56
Diazonamide Synthesis Studies: Use of Negishi Coupling to Fashion Diazonamide-Related Biaryls with Defined Axial Chirality Ken S. Feldman, Kyle J. Eastman, Guillaume Lessène Organic Letters	2002	50
Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies Kanak Raina, Chris D. Forbes, Rebecca Stronk, Cell chemical biology Tumor BiologyDrug TargetingMedicineCancer Cell BiologyCancer Selective Therapies	2024	50
Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively Kanak Raina, Chris D. Forbes, Rebecca Stronk,	2023	33
A Proposal for the Mechanism-of-Action of Diazoparaquinone Natural Products Ken S. Feldman, Kyle J. Eastman Journal of the American Chemical Society Diazoparaquinone Natural ProductsMedicinal ChemistryRepresentative Diazoparaquinone PrekinamycinHeterocyclicBiochemistry	2005	30
Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor Kyle Parcella, Kyle J. Eastman, Kap‐Sun Yeung, ACS Medicinal Chemistry Letters	2017	25
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase Kyle J. Eastman, Kyle Parcella, Kap‐Sun Yeung, MedChemComm	2017	18
Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity Venkat R. Gadhachanda, Kyle J. Eastman, Qiuping Wang, Bioorganic & Medicinal Chemistry Letters BiochemistryLow PicomolarViral HepatitisMedicineNatural Sciences	2018	12

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