Structural Basis for Substrate Specificity of Mammalian Neuraminidases

Victoria Smutova, Amgad Albohy, Xuefang Pan, +5

PLoS ONE

Insight into substrate recognition and catalysis by the human neuraminidase 3 (NEU3) through molecular modeling and site-directed mutagenesis

Amgad Albohy, Matthew Li, Ruixiang Blake Zheng, +2

Glycobiology

Dynamic Regulation of CD45 Lateral Mobility by the Spectrin-Ankyrin Cytoskeleton of T Cells

Christopher W. Cairo, Raibatak Das, Amgad Albohy, +5

Journal of Biological Chemistry

Cd45 ImmobilizationImmune RegulationImmunologyMolecular BiologyCytoskeleton +17

Substrate Recognition of the Membrane-Associated Sialidase NEU3 Requires a Hydrophobic Aglycone

Mahendra Sandbhor, Naoto Soya, Amgad Albohy, +5

Biochemistry

Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4

Amgad Albohy, Yi Zhang, Victoria Smutova, +2

ACS Medicinal Chemistry Letters

Drug TargetAntiparasitic AgentPharmacotherapyChemical BiologyMolecular Pharmacology +14

Lonazolac analogues: molecular modeling, synthesis, and in vivo anti-inflammatory activity

Mohamed A.H. Ismail, Jochen Lehmann, Dalal A. Abou El Ella, +2

Medicinal Chemistry Research

Lonazolac AnaloguesMedicineImmunologyMechanism Of ActionPharmacological Agent +5

Identification of Selective Inhibitors for Human Neuraminidase Isoenzymes Using C4,C7-Modified 2-Deoxy-2,3-didehydro-<i>N</i>-acetylneuraminic Acid (DANA) Analogues

Yi Zhang, Amgad Albohy, Yao Zou, +3

Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryNatural Sciences +11

Natural coumarins as potential anti-SARS-CoV-2 agents supported by docking analysis

Usama Ramadan Abdelmohsen, Amgad Albohy, Basma S. Abdulrazik, +5

RSC Advances

Molecular DockingAntiviral CompoundBiochemistryMedicineAntiviral Drug Development +11

Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes

Amgad Albohy, Sankar Mohan, Ruixiang Blake Zheng, +2

Bioorganic & Medicinal Chemistry

Molecular VirologyInhibitor SelectivityMedicineAntiviral Drug DevelopmentAntiviral Therapy +8

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-<i>s</i>-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades

Ihab Shawish, Assem Barakat, Ali Aldalbahi, +10

ACS Omega