<i>Drosophila</i> molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2

Fernando Mendive, Tom Van Loy, Sylvie Claeysen, +6

FEBS Letters

<i>Lgr4</i> is required for Paneth cell differentiation and maintenance of intestinal stem cells <i>ex vivo</i>

Roxana C. Mustata, Tom Van Loy, Anne Lefort, +4

EMBO Reports

Cell LineagePaneth Cell DifferentiationDevelopmental BiologyMedicineGene Expression +10

Myoinhibiting peptides are the ancestral ligands of the promiscuous Drosophila sex peptide receptor

Jeroen Poels, Tom Van Loy, Hans Peter Vandersmissen, +4

Cellular and Molecular Life Sciences

Developmental BiologySignal TransductionGeneticsReceptor (Biochemistry)Neuropeptide Receptor +7

An evolutionary comparison of leucine-rich repeat containing G protein-coupled receptors reveals a novel LGR subtype

Matthias B. Van Hiel, Hans Peter Vandersmissen, Tom Van Loy, +1

Peptides

Signal TransductionMolecular PhysiologyFunctional SelectivityG Protein-coupled ReceptorReceptor (Biochemistry) +9

Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions

Vladimir Bobkov, Aurélien Zarca, Anneleen Van Hout, +12

Biochemical Pharmacology

JC Virus Quasispecies Analysis Reveals a Complex Viral Population Underlying Progressive Multifocal Leukoencephalopathy and Supports Viral Dissemination via the Hematogenous Route

Tom Van Loy, Kim Thys, Caroline F. Ryschkewitsch, +5

Journal of Virology

CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry

Anneleen Van Hout, A. Klarenbeek, Vladimir Bobkov, +15

Biochemical Pharmacology

Hiv EntryHuman RetrovirusImmunologyAntiviral ResponseHiv +1

cDNA cloning and transcript distribution of two novel members of the neuroparsin family in the desert locust, <i>Schistocerca gregaria</i>

Ilse Claeys, Gert Simonet, Tom Van Loy, +2

Insect Molecular Biology

Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors

Anneleen Van Hout, Thomas D’huys, Merel Oeyen, +2

PLoS ONE

Drug TargetChemokine BiologyImmunologyImmunologic MechanismBiological Therapy +19

Evolutionary conservation of bursicon in the animal kingdom

Tom Van Loy, Matthias B. Van Hiel, Hans Peter Vandersmissen, +4

General and Comparative Endocrinology

BiologyEx-situ ConservationNatural SciencesMammalogyEvolutionary Biology +4