Volkmar Wehner

Evidence for CCl/CBr⋅⋅⋅π Interactions as an Important Contribution to Protein–Ligand Binding Affinity

Hans Matter, Marc Nazaré, Stefan Güssregen et al. · Angewandte Chemie International Edition · 2009 · 270 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold:  A Study Combining Structure-Activity Relationship and X-ray Crystallography

Marc Nazaré, David W. Will, Hans Matter et al. · Journal of Medicinal Chemistry · 2005 · 119 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of an Orally Active Non-Peptide Fibrinogen Receptor Antagonist Based on the Hydantoin Scaffold

Hans Ulrich Stilz, Wolfgang Guba, Bernd Jablonka et al. · Journal of Medicinal Chemistry · 2001 · 67 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Structural Requirements for Factor Xa Inhibition by 3-Oxybenzamides with Neutral P1 Substituents:  Combining X-ray Crystallography, 3D-QSAR, and Tailored Scoring Functions

Hans Matter, David W. Will, Marc Nazaré et al. · Journal of Medicinal Chemistry · 2005 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Fragment Deconstruction of Small, Potent Factor Xa Inhibitors: Exploring the Superadditivity Energetics of Fragment Linking in Protein–Ligand Complexes

Marc Nazaré, Hans Matter, David W. Will et al. · Angewandte Chemie International Edition · 2011 · 57 citations

Pharmacy, Chemistry, Pharmacology +13