Christine A. Sedore

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

Mark Lucanic, W. Todd Plummer, Esteban Chen et al. · Nature Communications · 2017 · 147 citations · Full text

Metformin treatment of diverse <i>Caenorhabditis</i> species reveals the importance of genetic background in longevity and healthspan extension outcomes

Brian Onken, Christine A. Sedore, Anna L Coleman-Hulbert et al. · Aging Cell · 2021 · 43 citations · Full text

Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions

Stephen A. Banse, Mark Lucanic, Christine A. Sedore et al. · GeroScience · 2019 · 35 citations · Full text

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Stephen A. Banse, E. Grace Jackson, Christine A. Sedore et al. · Aging · 2024 · 22 citations · Full text

Caenorhabditis Intervention Testing Program: the tyrosine kinase inhibitor imatinib mesylate does not extend lifespan in nematodes

Anna L Coleman-Hulbert, Erik Johnson, Christine A. Sedore et al. · PubMed · 2019 · 14 citations · Full text