Sébastien Letard

Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT

Patrice Dubreuil, Sébastien Letard, Marco A. Ciufolini et al. · PLoS ONE · 2009 · 412 citations · Full text

Medicine, Oncology, Pharmacology +15

Effect of tyrosine kinase inhibitor STI571 on the kinase activity of wild-type and various mutated c-kit receptors found in mast cell neoplasms

Yaël Zermati, Paulo De Sepulveda, Frédéric Féger et al. · Oncogene · 2003 · 189 citations

Life Sciences, Immunology, Molecular Biology +17

Gain-of-Function Mutations in the Extracellular Domain of KIT Are Common in Canine Mast Cell Tumors

Sébastien Letard, Ying Yang, Katia Hanssens et al. · Molecular Cancer Research · 2008 · 184 citations

Medicine, Molecular Genetics, Oncology +17

In aggressive forms of mastocytosis, TET2 loss cooperates with c-KITD816V to transform mast cells

Erinn Soucié, Katia Hanssens, Thomas Mercher et al. · Blood · 2012 · 99 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Suppressor of Cytokine Signaling 6 Associates with KIT and Regulates KIT Receptor Signaling

J Bayle, Sébastien Letard, Ronald Frank et al. · Journal of Biological Chemistry · 2004 · 92 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15