Hilary B. Schock

Mutational Anatomy of an HIV-1 Protease Variant Conferring Cross-resistance to Protease Inhibitors in Clinical Trials

Hilary B. Schock, Victor M. Garsky, Lawrence C. Kuo · Journal of Biological Chemistry · 1996 · 154 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Three-dimensional Structure of a Mutant HIV-1 Protease Displaying Cross-resistance to All Protease Inhibitors in Clinical Trials

Zhongguo Chen, Ying Li, Hilary B. Schock et al. · Journal of Biological Chemistry · 1995 · 109 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Plasmid DNA vaccines: assay for integration into host genomic DNA.

Brian J. Ledwith, Sujata Manam, Philip J. Troilo et al. · PubMed · 2000 · 79 citations

Veterinary Medicine, Molecular Biology, Molecular Genetics +17

Non-active Site Changes Elicit Broad-based Cross-resistance of the HIV-1 Protease to Inhibitors

David B. Olsen, Mark W. Stahlhut, Carrie A. Rutkowski et al. · Journal of Biological Chemistry · 1999 · 74 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

An alternate binding site for the P1–P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease

Sanjeev Munshi, Zhongguo Chen, Youwei Yan et al. · Acta Crystallographica Section D Biological Crystallography · 2000 · 42 citations

Life Sciences, Biochemistry, Pharmacology +14