Concepedia

Karin Brown

KB

4

Publications

626

Citations

4

H-Index

2012

Active since

Affiliations

Array BioPharma (United States)(Current)

Karin Brown is an author at Array BioPharma (United States) specializing in drug discovery, peptide science, and molecular modeling.

Top concepts

MedicineBiochemistryPharmacologyDrug DiscoveryPeptide ScienceSmall MoleculesNatural SciencesMolecular ModelingMolecular PharmacologyDerivatives

Publications per year

2012–2020

4

Publications

4

Identification of the Clinical Development Candidate <b>MRTX849</b>, a Covalent KRAS<sup>G12C</sup> Inhibitor for the Treatment of Cancer

Jay B. Fell, John P. Fischer, Brian R. Baer et al. · Journal of Medicinal Chemistry · 2020 · 559 citations · Full text

Discovery of 7-Tetrahydropyran-2-yl Chromans: β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors That Reduce Amyloid β-Protein (Aβ) in the Central Nervous System

Allen A. Thomas, Kevin W. Hunt, Matthew Volgraf et al. · Journal of Medicinal Chemistry · 2014 · 38 citations · Full text

7-Tetrahydropyran-2-yl Chromans, Peptide Science, Neurochemical Biomarkers +20

8-Tetrahydropyran-2-yl Chromans: Highly Selective Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors

Allen A. Thomas, Kevin W. Hunt, Brad Newhouse et al. · Journal of Medicinal Chemistry · 2014 · 18 citations · Full text

Pharmaceutical Science, Molecular Biology, Peptide Science +20

Identification of Alpha 1-Acid Glycoprotein (AAG) As a Potential Patient Selection Biomarker for Improved Clinical Activity of the Novel KSP Inhibitor ARRY-520 in Relapsed and Refractory Multiple Myeloma (MM)

Brian Tunquist, Karin Brown, Gary P. Hingorani et al. · Blood · 2012 · 11 citations

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