Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

Esra A. Akbay, Shohei Koyama, Julián Carretero, +24

Cancer Discovery

Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis

Alice T. Shaw, Beow Y. Yeap, Benjamin Solomon, +20

The Lancet Oncology

Overall SurvivalAlk Gene RearrangementMedicineRetrospective AnalysisPathology +5

Noninvasive Detection of Response and Resistance in <i>EGFR</i> -Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA

Geoffrey R. Oxnard, Cloud P. Paweletz, Yanan Kuang, +8

Clinical Cancer Research

A Novel ALK Secondary Mutation and EGFR Signaling Cause Resistance to ALK Kinase Inhibitors

Takaaki Sasaki, Jussi Koivunen, Atsuko Ogino, +23

Cancer Research

ImmunologyAnaplastic Lymphoma KinaseTumor BiologyDrug ResistanceSignaling Pathway +14

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer

Aria Vaishnavi, Marzia Capelletti, Anh T. Le, +21

Nature Medicine

Oncogenic AgentPathologyCancer GeneticsMedicineLung Cancer +1

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Chen Zhao, Katherine A. Cheng, Zandra E. Walton, +40

Nature

OncologyOncogenic AgentMedicineImmunologyTherapeutic Response +7

Clinical, Pathologic, and Biologic Features Associated with <i>BRAF</i> Mutations in Non–Small Cell Lung Cancer

Stephanie Cardarella, Atsuko Ogino, Mizuki Nishino, +7

Clinical Cancer Research

Natural History and Molecular Characteristics of Lung Cancers Harboring EGFR Exon 20 Insertions

Geoffrey R. Oxnard, Peter Lo, Mizuki Nishino, +6

Journal of Thoracic Oncology

OncologyMedicineNatural HistoryPathologyCancer Genomics +7

Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

Dalia Ercan, Chunxiao Xu, Masahiko Yanagita, +20

Cancer Discovery

Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer

Antonio Calles, Xiaoyun Liao, Lynette M. Sholl, +9

Journal of Thoracic Oncology