MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles

Nicolas Menzel, Wolfgang Fischl, Kathrin Hueging, +7

PLoS Pathogens

Viral ReplicationHepatitis C VirusImmunologyViral HepatitisPla2g4a-dependent Lipolysis +14

A Plant-Derived Flavonoid Inhibits Entry of All HCV Genotypes Into Human Hepatocytes

Sibylle Haid, Alexandra Novodomská, Juliane Gentzsch, +16

Gastroenterology

HepatologyBiochemistryViral HepatitisLiver PhysiologyMedicine +8

Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment

Juliane Gentzsch, Christiane Brohm, Eike Steinmann, +7

PLoS Pathogens

Capsid AssemblyHcv MorphogenesisVirus StructureViral ReplicationMolecular Virology +12

Subcellular Localization and Function of an Epitope-Tagged p7 Viroporin in Hepatitis C Virus-Producing Cells

Gabrielle Vièyres, Christiane Brohm, Martina Friesland, +5

Journal of Virology

Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity

Juliane Gentzsch, Bettina Hinkelmann, Lars Kaderali, +5

Antiviral Research

Hepatitis CViral HepatitisAntiviral ActivityBioanalysisAntiviral Drug Development +8

Strong induction of 4-1BB, a growth and survival promoting costimulatory receptor, in HTLV-1–infected cultured and patients' T cells by the viral Tax oncoprotein

Klemens Pichler, Tarek Kattan, Juliane Gentzsch, +4

Blood

High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants

Jonas Kügler, Stefan Schmelz, Juliane Gentzsch, +7

Journal of Biological Chemistry

BiochemistryNatural SciencesPeptide LibraryAntiviral Drug DevelopmentCommon Resistant Mutants +9

ABHD5/CGI-58, the Chanarin-Dorfman Syndrome Protein, Mobilises Lipid Stores for Hepatitis C Virus Production

Gabrielle Vièyres, Kathrin Welsch, Gisa Gerold, +5

PLoS Pathogens

Proteinlipid InteractionHepatitis C VirusMolecular BiologyAnalytical UltracentrifugationMobilises Lipid Stores +15

Bile Acids Specifically Increase Hepatitis C Virus RNA-Replication

Patrick Chhatwal, Dorothea Bankwitz, Juliane Gentzsch, +4

PLoS ONE

Completion of Hepatitis C Virus Replication Cycle in Heterokaryons Excludes Dominant Restrictions in Human Non-liver and Mouse Liver Cell Lines

Anne Frentzen, Kathrin Hüging, Julia Bitzegeio, +10

PLoS Pathogens

Hcv PropagationViral ReplicationHepatitis C VirusGeneticsImmunology +17