Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses

Laurent Chatel‐Chaix, Mirko Cortese, Inés Romero‐Brey, +9

Cell Host & Microbe

BiologyPathogenesisImmunologyViral PathogenesisInnate Immune Responses +6

Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins

Pietro Scaturro, Mirko Cortese, Laurent Chatel‐Chaix, +2

PLoS Pathogens

Viral Rna ReplicationVirus StructureCrystal StructureViral ReplicationProtein Folding +13

Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

Christian Steuer, Christian Gege, Wolfgang Fischl, +3

Bioorganic & Medicinal Chemistry

BiochemistryDengue Virus ProteaseAntiviral ActivityMedicineAntiviral Drug Development +6

MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles

Nicolas Menzel, Wolfgang Fischl, Kathrin Hueging, +7

PLoS Pathogens

Viral ReplicationHepatitis C VirusImmunologyViral HepatitisPla2g4a-dependent Lipolysis +14

A reversible gene trap collection empowers haploid genetics in human cells

Tilmann Bürckstümmer, Carina Banning, Philipp Hainzl, +32

Nature Methods

Human CellsGeneticsGenomic MechanismGenetic MechanismMolecular Genetics +4

High-Throughput Screening Using Dengue Virus Reporter Genomes

Wolfgang Fischl, Ralf Bartenschlager

Methods in molecular biology

A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication

Laurent Chatel‐Chaix, Wolfgang Fischl, Pietro Scaturro, +5

Journal of Virology

Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2’-O-Methylation Mutant

Bianca Schmid, Melanie Rinas, Alessia Ruggieri, +9

PLoS Pathogens

Viral ReplicationDengue VirusImmunologyViral PathogenesisMolecular Biology +15

Cellular N-myristoyltransferases play a crucial picornavirus genus-specific role in viral assembly, virion maturation, and infectivity

Irena Corbic Ramljak, Julia Stanger, Antonio Real-Hohn, +8

PLoS Pathogens

Viral ReplicationViral Maturation CleavageVirion MaturationSynthetic VirologyMolecular Biology +15

Changing the Protease Specificity for Activation of a Flavivirus, Tick-Borne Encephalitis Virus

Wolfgang Fischl, Sigrid Elshuber, Sabrina Schrauf, +1

Journal of Virology

Maturation ProcessMolecular VirologyMedicineNatural SciencesPathogenesis +13