Rutger D. Douma

An Engineered Yeast Efficiently Secreting Penicillin

Loknath Gidijala, Jan A.K.W. Kiel, Rutger D. Douma et al. · PLoS ONE · 2009 · 89 citations · Full text

Life Sciences, Biotechnology, Microbiology +17

Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum

Lodewijk P. de Jonge, Rutger D. Douma, Joseph J. Heijnen et al. · Metabolomics · 2011 · 67 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Intracellular metabolite determination in the presence of extracellular abundance: Application to the penicillin biosynthesis pathway in <i>Penicillium chrysogenum</i>

Rutger D. Douma, Lodewijk P. de Jonge, Caspar T. H. Jonker et al. · Biotechnology and Bioengineering · 2010 · 62 citations

Life Sciences, Biochemistry, Microbiology +11

Dynamic gene expression regulation model for growth and penicillin production in <i>Penicillium chrysogenum</i>

Rutger D. Douma, Peter J.T. Verheijen, Wim T. A. M. de Laat et al. · Biotechnology and Bioengineering · 2010 · 55 citations

Life Sciences, Biochemistry, Microbiology +17

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

Rutger D. Douma, Joana M Batista, Kai M Touw et al. · BMC Systems Biology · 2011 · 39 citations · Full text

Life Sciences, Biotechnology, Microbiology +14