Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

Philip J. M. Brouwer, Tom G. Caniels, Karlijn van der Straten, +30

Science

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

Sandhya Bangaru, Gabriel Ozorowski, Hannah L. Turner, +15

Science

VaccinationAdvanced Vaccine CandidateVirus StructureVaccine DevelopmentSpike Trimers +12

A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface

Sandhya Bangaru, Shanshan Lang, Michael Schotsaert, +14

Cell

ImmunologyVirologyInfluenza VaccineFlu VaccinationVirus Transmission +1

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity

Hejun Liu, Nicholas C. Wu, Meng Yuan, +11

Immunity

An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain

Nicholas C. Wu, Meng Yuan, Hejun Liu, +10

Cell Reports

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

Philip J. M. Brouwer, Tom G. Caniels, Karlijn van der Straten, +30

Vaccine DevelopmentNon-rbd EpitopesVaccine ResearchVaccine TargetVaccine Surveillance +13

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

Jeroen M. J. Tas, Jahyun Koo, Ying‐Cing Lin, +25

Immunity

Adaptive Immune SystemHumoral ResponseImmunologyImmunodominanceImmunologic Mechanism +17

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, +37

Science Translational Medicine

A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA

Sandhya Bangaru, H. Zhang, Iuliia M. Gilchuk, +15

Nature Communications

Structure and immune recognition of the porcine epidemic diarrhea virus spike protein

Robert N. Kirchdoerfer, Mahesh Bhandari, Olnita Martini, +4

Structure

Virus StructurePathogenesisViral PathogenesisImmunologyVirology +5