Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation

Sylvia Weilner, Susanna Skalicky, Benjamin Salzer, +9

Bone

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

Sabine Heitzeneder, Kristopher R. Bosse, Zhongyu Zhu, +38

Cancer Cell

Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function

Benjamin Salzer, Christina M. Schueller, Charlotte U. Zajc, +12

Nature Communications

Combinatorial Antigen RecognitionAvidcar PlatformReversible ControlT CellsMedicine +13

A conformation-specific ON-switch for controlling CAR T cells with an orally available drug

Charlotte U. Zajc, Markus Dobersberger, Irene Schaffner, +11

Proceedings of the National Academy of Sciences

Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors

Jake Burton, Jesús A. Siller‐Farfán, Johannes Pettmann, +4

Proceedings of the National Academy of Sciences

A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells in Vivo

Susana Pascoal, Benjamin Salzer, Eva Scheuringer, +6

Cancers

Laboratory ImmunologyImmunologyImmunologic MechanismT CellsCell Specialization +18

The frequency of differentiated CD3+CD27-CD28- T cells predicts response to CART cell therapy in diffuse large B-cell lymphoma

Nina Worel, Katharina Grabmeier‐Pfistershammer, Bernhard Kratzer, +20

Frontiers in Immunology

The ligand-dependent suppression of TCR signaling by the immune checkpoint receptor LAG3 depends on the cytoplasmic RRFSALE motif

Katharina Radakovics, Annika De Sousa Linhares, Benjamin Salzer, +6

Science Signaling

Reporter Cell ActivationT-regulatory CellImmunologyImmune RegulationCell Death +18

A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells

Charlotte U. Zajc, Julia Proff, Natascha Teufert, +7

Scientific Reports

Directed Evolution of Stabilized Monomeric CD19 for Monovalent CAR Interaction Studies and Monitoring of CAR-T Cell Patients

Elisabeth Laurent, Anna Sieber, Benjamin Salzer, +9

ACS Synthetic Biology

Cell TherapyT-regulatory CellImmunologyAntigen ProcessingImmunotherapy +14