Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

Anatoly V. Rubtsov, Kira Rubtsova, Aryeh Fischer, +4

Blood

T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance

Kira Rubtsova, Anatoly V. Rubtsov, Linda F. van Dyk, +2

Proceedings of the National Academy of Sciences

Efficient Antibody IsotypeAdaptive Immune SystemT-regulatory CellImmunologyImmune Regulation +24

B cells expressing the transcription factor T-bet drive lupus-like autoimmunity

Kira Rubtsova, Anatoly V. Rubtsov, Joshua M. Thurman, +3

Journal of Clinical Investigation

ImmunogeneticsAutoimmune DiseaseSystemic Lupus ErythematosusSystemic Lupus Erythematosus TreatmentLupus +13

CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs

Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, +3

The Journal of Immunology

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

Shaodong Dai, Eric S. Huseby, Kira Rubtsova, +5

Immunity

Germline RulesSignal TransductionT-regulatory CellImmunologyAntigen Processing +7

Development of Tbet- and CD11c-expressing B cells in a viral infection requires T follicular helper cells outside of germinal centers

Wenzhi Song, Olivia Q. Antao, Emily Condiff, +10

Immunity

Germinal CentersLymphocyte DevelopmentPathogenesisImmunologyCd11c-expressing B Cells +7

TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice

Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, +1

Immunologic Research

InflammationAutoimmune DiseaseAllergyAutoantibody ProductionImmune Cell Development +7

A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers

Lei Yin, Eric S. Huseby, James Scott‐Browne, +6

Immunity

HistocompatibilitySignal TransductionT-regulatory CellImmunologyAntigen Processing +5

T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses

Kira Rubtsova, Anatoly V. Rubtsov, Kalani Halemano, +4

PLoS ONE

T Cell ProductionAdaptive Immune SystemImmunodeficienciesImmunologyImmune Regulation +20

JAK-STAT signaling pathways are activated in the brain following reovirus infection

Robin J Goody, J. David Beckham, Kira Rubtsova, +1

Journal of NeuroVirology

Jak-stat Signaling PathwaysMolecular VirologyNeurovirologyMedicinePathogenesis +9