John H. Merrett

Rational Design of Peptide-Based HIV Proteinase Inhibitors

Noel A. Roberts, Joseph A. Martin, Derek Kinchington et al. · Science · 1990 · 922 citations

Immunology, Antiviral Drug, Medicinal Chemistry +17

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Klaus Klumpp, Vincent Lévêque, Sophie Le Pogam et al. · Journal of Biological Chemistry · 2005 · 215 citations · Full text

Use of a Pharmacophore Model To Discover a New Class of Influenza Endonuclease Inhibitors

K. E. B. PARKES, Philipp Ermert, Jürg Fässler et al. · Journal of Medicinal Chemistry · 2003 · 141 citations · Full text

Cell Culture, Antiviral Drug, Drug Resistance +16

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

David B. Smith, Joseph A. Martin, Klaus Klumpp et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 96 citations

Viral Replication, Biochemistry, Natural Sciences +11

Synthesis and antiviral activity of monofluoro and difluoro analogs of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1)

D. J. BUSHNELL, I. B. R. Duncan, Stephen J. Dunsdon et al. · Journal of Medicinal Chemistry · 1990 · 71 citations

Bioorganic Chemistry, Antiviral Drug, Human Immunodeficiency Virus +17