Dexamethasone Inhibits Inducible Nitric-Oxide Synthase Expression and Nitric Oxide Production by Destabilizing mRNA in Lipopolysaccharide-Treated Macrophages

Riku Korhonen, Aleksi Lahti, Mari Hämäläinen, +2

Molecular Pharmacology

c-Jun NH2-Terminal Kinase Inhibitor Anthra(1,9-cd)pyrazol-6(2H)-one Reduces Inducible Nitric-Oxide Synthase Expression by Destabilizing mRNA in Activated Macrophages

Aleksi Lahti, Ulla Jalonen, Hannu Kankaanranta, +1

Molecular Pharmacology

Inhibitors of Mitogen‐Activated Protein KinasesDownregulate COX‐2 Expression in Human Chondrocytes

Riina Nieminen, Sari Leinonen, Aleksi Lahti, +5

Mediators of Inflammation

Human ChondrocytesImmunologyPathologyCell DeathCox-2 Expression +18

Calcineurin inhibitors, cyclosporin A and tacrolimus inhibit expression of inducible nitric oxide synthase in colon epithelial and macrophage cell lines

Mari Hämäläinen, Aleksi Lahti, Eeva Moilanen

European Journal of Pharmacology

InflammationSignal TransductionTacrolimus Inhibit ExpressionGastrointestinal PharmacologyCalcineurin Inhibitors +9

Tumour Necrosis Factor-α Regulates Human Eosinophil Apoptosis via Ligation of TNF-Receptor 1 and Balance between NF-κB and AP-1

Hannu Kankaanranta, Pinja Ilmarinen, Xianzhi Zhang, +6

PLoS ONE

AsthmaApoptosisImmunologyImmune RegulationCell Death +14

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5

Xianzhi Zhang, Msc, Eeva Moilanen, +6

Journal of Allergy and Clinical Immunology

InflammationSignal TransductionMolecular PhysiologyNitric OxideApoptosis +10

JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages

Riina Nieminen, Aleksi Lahti, Ulla Jalonen, +2

International Immunopharmacology

InflammationCytokineSignaling PathwayCell RegulationImmunology +7

Inhibition of tristetraprolin expression by dexamethasone in activated macrophages

Ulla Jalonen, Aleksi Lahti, Riku Korhonen, +2

Biochemical Pharmacology

InflammationCytokineAnti-inflammatoryAutoimmune DiseaseActivated Macrophages +6

Bi-directional effects of the elevation of intracellular calcium on the expression of inducible nitric oxide synthase in J774 macrophages exposed to low and to high concentrations of endotoxin

Riku Korhonen, Hannu Kankaanranta, Aleksi Lahti, +3

Biochemical Journal

Inhibition of p38 mitogen-activated protein kinase enhances c-Jun N-terminal kinase activity: Implication in inducible nitric oxide synthase expression

Aleksi Lahti, Outi Sareila, Hannu Kankaanranta, +1

BMC Pharmacology