Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation.

Shigeo Uotani, Jens Tornøe, Jeffrey S. Flier

Diabetes

Functional PropertiesAdipokinesGastrointestinal Peptide HormoneMolecular PharmacologyLeptin Internalization +20

Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery

Lars U. Wahlberg, Göran Lind, Per Almqvist, +8

Journal of neurosurgery

Transcellular Transport of Leptin by the Short Leptin Receptor Isoform ObRa in Madin-Darby Canine Kidney Cells*

Stanley M. Hileman, Jens Tornøe, Jeffrey S. Flier, +1

Endocrinology

Generation of a synthetic mammalian promoter library by modification of sequences spacing transcription factor binding sites

Jens Tornøe, Philip Kusk, Teit E. Johansen, +1

Gene

Systems BiologyEngineeringProtein ExpressionGene StructureGene Regulation +10

Efficient in vivo protection of nigral dopaminergic neurons by lentiviral gene transfer of a modified Neurturin construct

Lone Fjord‐Larsen, Jens Leander Johansen, Philip Kusk, +4

Experimental Neurology

MedicineSynaptic TransmissionNeurotransmitterPharmacologyNigral Dopaminergic Neurons +7

Long-term Delivery of Nerve Growth Factor by Encapsulated Cell Biodelivery in the Göttingen Minipig Basal Forebrain

Lone Fjord‐Larsen, Philip Kusk, Jens Tornøe, +7

Molecular Therapy

Generation and characterization of immortalized rat pancreatic stellate cells

Gisela Sparmann, Christine Hohenadl, Jens Tornøe, +8

American Journal of Physiology-Gastrointestinal and Liver Physiology

Cell LineagePancreatic CancerImmunologyImmortalized Pscs 7Pathology +12

Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer

Lone Fjord‐Larsen, Philip Kusk, Dwaine F. Emerich, +6

Gene Therapy

Regenerative MedicineNeuroregenerationCellular NeuroscienceMedicineCell Biodelivery +9

Encapsulated cell-based biodelivery of Meteorin is neuroprotective in the quinolinic acid rat model of neurodegenerative disease

Jens Tornøe, Malene Torp, Jesper Roland Jørgensen, +5

Restorative Neurology and Neuroscience

Encapsulated cell device approach for combined electrical stimulation and neurotrophic treatment of the deaf cochlea

Wiebke Konerding, Peter Hubka, Jens Tornøe, +5

Hearing Research

EngineeringBiomedical EngineeringStimulation DeviceHearing AidsCochlear Implant Communication +14