Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

Jonathan J. Lyons, Xiaomin Yu, Jason D. Hughes, +33

Nature Genetics

Basal Serum TryptaseClinical DisordersAllergyAutoimmune DiseasePathology +3

Broadly neutralizing antibodies target the coronavirus fusion peptide

Cherrelle Dacon, Courtney Tucker, Linghang Peng, +41

Science

VaccinationCandidate EpitopeVirus StructureVaccine TargetFusion Peptide +13

Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1

Jean‐Christophe Meunier, Ronald E. Engle, Kristina Faulk, +7

Proceedings of the National Academy of Sciences

ImmunologyViral PathogenesisApolipoprotein C1Cross-genotype NeutralizationAutoimmune Liver Disease +16

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern

Hyeseon Cho, Kristina Kay Gonzales-Wartz, Deli Huang, +37

Science Translational Medicine

A fungal protease allergen provokes airway hyper-responsiveness in asthma

Nariman Balenga, Michael Klichinsky, Zhihui Xie, +6

Nature Communications

ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans

Jonathan J. Lyons, Yan Liu, C.A. Ma, +22

The Journal of Experimental Medicine

Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice

Ying Chen, Cuiying Li, Dong Weng, +8

Toxicology and Applied Pharmacology

InflammationCytokineInflammatory DiseaseInflammatory Lung DiseaseLung Inflammation +9

Two interacting transcriptional coactivators cooperatively control plant immune responses

Huan Chen, Min Li, Guang Qi, +7

Science Advances

Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses

Cherrelle Dacon, Linghang Peng, Ting-Hui Lin, +41

Cell Host & Microbe

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation

Difeng Fang, Kairong Cui, Gangqing Hu, +10

The Journal of Experimental Medicine