Andrea J. Maichele

Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

Manfred T. Reetz, J r me J.-P. Peyralans, Andrea J. Maichele et al. · Chemical Communications · 2006 · 175 citations

Engineering, Biotechnology, Biocatalysis +12

Enhancing the Enantioselectivity of an Epoxide Hydrolase by Directed Evolution

Manfred T. Reetz, Claudia Torre, Andreas Eipper et al. · Organic Letters · 2003 · 156 citations

Life Sciences, Biochemistry, Biotechnology +17

Expanding the Substrate Scope of Enzymes: Combining Mutations Obtained by CASTing

Manfred T. Reetz, José Daniel Carballeira, Jérôme J.‐P. Peyralans et al. · Chemistry - A European Journal · 2006 · 147 citations

Life Sciences, Biochemistry, Biotechnology +17

Mutations in the testis/liver isoform of the phosphorylase kinase γ subunit (PHKG2) cause autosomal liver glycogenosis in the gsd rat and in humans

Andrea J. Maichele, Barbara Burwinkel, Irène Maire et al. · Nature Genetics · 1996 · 85 citations

Medicine, Genetics, Molecular Genetics +13

Directed evolution of enantioselective hybrid catalysts: a novel concept in asymmetric catalysis

Manfred T. Reetz, Martin Rentzsch, Andreas Pletsch et al. · Tetrahedron · 2007 · 81 citations

Natural Sciences, Chemical Engineering, Chemistry +17