David Toma

A Novel Pregnane X Receptor-mediated and Sterol Regulatory Element-binding Protein-independent Lipogenic Pathway

Jie Zhou, Yonggong Zhai, Ying Mu et al. · Journal of Biological Chemistry · 2006 · 357 citations · Full text

A Novel Constitutive Androstane Receptor-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification

S. P. S. Saini, Junichiro Sonoda, Li Xu et al. · Molecular Pharmacology · 2004 · 245 citations

Traditional Chinese Medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) Activate Pregnane X Receptor and Increase Warfarin Clearance in Rats

Ying Mu, Jinnan Zhang, Shimin Zhang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 165 citations

Orphan Nuclear Receptor Pregnane X Receptor Sensitizes Oxidative Stress Responses in Transgenic Mice and Cancerous Cells

Haibiao Gong, Shivendra V. Singh, Sharda P. Singh et al. · Molecular Endocrinology · 2005 · 110 citations

Lipid Peroxidation, Cell Death, Transgenic Mice +17

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice

Hirdesh Uppal, David Toma, S. P. S. Saini et al. · Hepatology · 2005 · 107 citations

Pxr Null Mice, Lipid Peroxidation, Pathology +18