Ellen Langille

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling

Sampath K. Loganathan, Krista Schleicher, Ahmad Malik et al. · Science · 2020 · 301 citations · Full text

Life Sciences, Genetics, Oncology +17

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

Nicole I. Park, Paul Guilhamon, Kinjal Desai et al. · Cell stem cell · 2017 · 221 citations

Medicine, Neuroscience, Oncology +17

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

Joel D. Pearson, Katherine Huang, Marek Pacal et al. · Cancer Cell · 2021 · 175 citations · Full text

Medicine, Cancer Biology, Oncology +9

Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer

Ellen Langille, Khalid N. Al‐Zahrani, Zhibo Ma et al. · Cancer Discovery · 2022 · 54 citations · Full text

Life Sciences, Genetics, Oncology +17

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, T. J. Cho, Saptaparna Mukherjee et al. · Molecular Systems Biology · 2024 · 23 citations · Full text

Medicine, Genetics, Oncology +16