Adam J. Dupuy

Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system

Adam J. Dupuy, Keiko Akagi, David A. Largaespada et al. · Nature · 2005 · 486 citations

Biology, Genetics, Molecular Genetics +6

Clonal selection drives genetic divergence of metastatic medulloblastoma

Xiaochong Wu, Paul A. Northcott, Adrian M. Dubuc et al. · Nature · 2012 · 410 citations

Somatic Variant, Tumor Heterogeneity, Medicine +5

Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse

Lara S. Collier, Corey M. Carlson, Shruthi Ravimohan et al. · Nature · 2005 · 406 citations

Somatic Variant, Health Sciences, Tumor Heterogeneity +11

A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

Timothy K. Starr, Raha Allaei, Kevin A.T. Silverstein et al. · Science · 2009 · 354 citations · Full text

Engineering, Genetics, Epigenetics +17

Gene transfer into genomes of human cells by the sleeping beauty transposon system

Aron M. Geurts, Ying Yang, Karl J. Clark et al. · Molecular Therapy · 2003 · 348 citations · Full text