Identification of the Maturation Factor for Dual Oxidase

Helmut Grasberger, Samuel Refetoff

Journal of Biological Chemistry

Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic Mice

Hiroko Nagao‐Kitamoto, Andrew B. Shreiner, Merritt Gillilland, +12

Cellular and Molecular Gastroenterology and Hepatology

InflammationChronic Inflammatory DiseasesMicrobiota FunctionDysbiosisMucosal Immunology +10

Activation of Dual Oxidases Duox1 and Duox2

Sabrina Rigutto, Candice Hoste, Helmut Grasberger, +6

Journal of Biological Chemistry

DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses

Simone Lipinski, Andreas Till, Christian Sina, +4

Journal of Cell Science

Ros GenerationInnate Immune SystemImmunologyCell DeathInnate Immunity +18

Biallelic Inactivation of the Dual Oxidase Maturation Factor 2 (DUOXA2) Gene as a Novel Cause of Congenital Hypothyroidism

I. Zamproni, Helmut Grasberger, Francesca Cortinovis, +8

The Journal of Clinical Endocrinology & Metabolism

Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine

Helmut Grasberger, Jun Gao, Hiroko Nagao‐Kitamoto, +9

Gastroenterology

InflammationDysbiosisImmune HomeostasisAllergyMucosal Immunology +9

Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut

Sho Kitamoto, Christopher J. Alteri, Michael Rodrigues, +23

Nature Microbiology

BiologyNutritionDysbiosisInflamed GutGut Microbiology +9

Dual Oxidases Control Release of Hydrogen Peroxide by the Gastric Epithelium to Prevent Helicobacter felis Infection and Inflammation in Mice

Helmut Grasberger, Mohamad El‐Zaatari, Duyen T. Dang, +1

Gastroenterology

InflammationLipid PeroxidationImmunologyGastroenterologyHelicobacter Felis Infection +8

A Familial Thyrotropin (TSH) Receptor Mutation Provides in Vivo Evidence that the Inositol Phosphates/Ca2+ Cascade Mediates TSH Action on Thyroid Hormone Synthesis

Helmut Grasberger, Jacqueline Van Sande, Ahmad Hag-Dahood Mahameed, +2

The Journal of Clinical Endocrinology & Metabolism

Mice Deficient in Dual Oxidase Maturation Factors Are Severely Hypothyroid

Helmut Grasberger, Xavier De Deken, Olga Barca‐Mayo, +4

Molecular Endocrinology

GeneticsLipid PeroxidationRedox BiologyOxidative StressMetabolism +15