Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

Ebru Erbay, Vladimir R. Babaev, Jared R. Mayers, +8

Nature Medicine

InflammationMacrophage Lipid ChaperoneOxysterolBiochemistryCell Signaling +8

Universal DNA methylation age across mammalian tissues

Ake T. Lu, Zhe Fei, Amin Haghani, +184

Nature Aging

A genetic variant at the fatty acid-binding protein <i>aP2</i> locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease

Gürol Tuncman, Ebru Erbay, X. Hom, +3

Proceedings of the National Academy of Sciences

Metabolic DisorderGeneticsGenetic EpidemiologyInsulin SignalingObesity +14

Targeting IRE1 with small molecules counteracts progression of atherosclerosis

Özlem Tufanlı, Pelin Telkoparan‐Akillilar, Diego Acosta‐Alvear, +7

Proceedings of the National Academy of Sciences

IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients

Ebru Erbay, In-Hyun Park, Paul D. Nuzzi, +2

The Journal of Cell Biology

Universal DNA methylation age across mammalian tissues

Aimei Lu, Zhe Fei, Amin Haghani, +184

AgingEpigenetic ChangeGeneticsDna MethylationMolecular Genetics +14

The Mammalian Target of Rapamycin Regulates C2C12 Myogenesis via a Kinase-independent Mechanism

Ebru Erbay, Jie Chen

Journal of Biological Chemistry

Molecular RegulationCellular PhysiologyMammalian TargetSkeletal Muscle DifferentiationSignaling Pathway +14

Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation

İsmail Çimen, Begüm Kocatürk, Seda Koyuncu, +9

Science Translational Medicine

Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis

Gantsetseg Tumurkhuu, Jargalsaikhan Dagvadorj, Rebecca A. Porritt, +6

Cell Metabolism

InflammationChlamydia Pneumoniae HijacksPathogenesisImmunologyAutoinflammatory Disease +3

Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis

Umut İnci Onat, Özlem Tufanlı, İsmail Çimen, +10

Journal of the American College of Cardiology