Béatrice Josselin

Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3

Killian Oukoloff, Nicolas Coquelle, Manuela Bartolini et al. · European Journal of Medicinal Chemistry · 2019 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Helmi Tazarki, Waël Zeinyeh, Yannick J. Esvan et al. · European Journal of Medicinal Chemistry · 2019 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency

Nada Ibrahim, Pascal Bonnet, Jean‐Daniel Brion et al. · European Journal of Medicinal Chemistry · 2020 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Design of new disubstituted imidazo[1,2-<i>b</i>]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation

Jonathan Elie, Omid Feizbakhsh, Nathalie Desban et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2020 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase

C. Juillet, Ludmila Ermolenko, Dina V. Boyarskaya et al. · Journal of Medicinal Chemistry · 2021 · 20 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17