Discovery of potential Q-marker of traditional Chinese medicine based on plant metabolomics and network pharmacology: Periplocae Cortex as an example

Ziting Li, Fengxiang Zhang, Cailian Fan, +5

Phytomedicine

Network PharmacologyBiochemistryTraditional Chinese MedicineMedicineBioanalysis +9

Qi-Li-Qiang-Xin Alleviates Isoproterenol-Induced Myocardial Injury by Inhibiting Excessive Autophagy via Activating AKT/mTOR Pathway

Cailian Fan, Xiyang Tang, Meng‐nan Ye, +4

Frontiers in Pharmacology

The discovery of Q-markers of Qiliqiangxin Capsule, a traditional Chinese medicine prescription in the treatment of chronic heart failure, based on a novel strategy of multi-dimensional “radar chart” mode evaluation

Liangliang He, Yuehe Liu, Kefeng Yang, +7

Phytomedicine

Heart FailureChronic Heart FailureNovel StrategyCardiovascular DiseaseQiliqiangxin Capsule +5

Fuziline alleviates isoproterenol‐induced myocardial injury by inhibiting ROS‐triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway

Cailian Fan, Zhihong Yao, Meng‐nan Ye, +4

Journal of Cellular and Molecular Medicine

Systematic screening and characterization of Qi-Li-Qiang-Xin capsule-related xenobiotics in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry

Weijing Yun, Zhihong Yao, Cailian Fan, +5

Journal of Chromatography B

Ultra-performance Liquid ChromatographyQi-li-qiang-xin Capsule-related XenobioticsBiochemistryMedicineSystematic Screening +7

Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK/mTOR pathway in vitro

Cailian Fan, Wanjun Cai, Meng‐nan Ye, +2

Journal of Integrative Medicine

InflammationAutophagic Cell DeathTraditional Chinese MedicineMedicineHerbal Medicine +9

Pharmacokinetics, hepatic disposition, and heart tissue distribution of 14 compounds in rat after oral administration of Qi‐Li‐Qiang‐Xin capsule via ultra‐high‐performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry

Xiyang Tang, Zi-qin Dai, Jiaxing Zeng, +5

Journal of Separation Science

Heart Tissue DistributionGinsenoside Rb1Pharmacological StudyDrug DiscoveryQi‐li‐qiang‐xin Capsule +11

Therapeutic potential of alkaloid extract from Codonopsis Radix in alleviating hepatic lipid accumulation: insights into mitochondrial energy metabolism and endoplasmic reticulum stress regulation in NAFLD mice

Cailian Fan, Guan Wang, M. L. Chen, +3

Chinese Journal of Natural Medicines

Codonopsis RadixBiochemistryMedicineLiver PhysiologyLipid Peroxidation +9

Targeted isolation and identification of bioactive pyrrolidine alkaloids from Codonopsis pilosula using characteristic fragmentation-assisted mass spectral networking

Xiyang Tang, Cailian Fan, Jiaxing Zeng, +7

Chinese Journal of Natural Medicines

Bioorganic ChemistryBiochemistryCodonopsis PilosulaNatural SciencesMedicine +8

A new cinnamamide derivative and two new β-carboline alkaloids from the stems of Picrasma quassioides

Jie Zhang, Chuanxi Wang, Xiaojun Song, +6

Fitoterapia

Picrasma QuassioidesBiochemistryMedicineSecondary MetaboliteNew Cinnamamide +5