Jeffrey Klarenbeek

Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity

Jeffrey Klarenbeek, Joachim Goedhart, Aernoud van Batenburg et al. · PLoS ONE · 2015 · 323 citations · Full text

Natural Sciences, Biophysics, Cell Biology +15

A mTurquoise-Based cAMP Sensor for Both FLIM and Ratiometric Read-Out Has Improved Dynamic Range

Jeffrey Klarenbeek, Joachim Goedhart, Mark A. Hink et al. · PLoS ONE · 2011 · 210 citations · Full text

Natural Sciences, Biochemistry, Molecular Biology +17

A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells

Arnold H. van der Luit, Stefan R. Vink, Jeffrey Klarenbeek et al. · Molecular Cancer Therapeutics · 2007 · 138 citations · Full text

Medicine, Oncology, Pharmacology +16

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors

Daniela Leyton-Puig, Tadamoto Isogai, Elisabetta Argenzio et al. · Nature Communications · 2017 · 123 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts

Arnold H. van der Luit, Marianne Budde, Shuraila F. Zerp et al. · Biochemical Journal · 2006 · 84 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17