Vipulkumar K. Patel

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA ₂ Inhibitor

Nicholas D. Measom, Kenneth Down, David J. Hirst et al. · ACS Medicinal Chemistry Letters · 2016 · 246 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis of the potent influenza neuraminidase inhibitor 4-guanidino Neu5Ac2en. X-Ray molecular structure of 5-acetamido-4-amino-2,6-anhydro-3,4,5-trideoxy-D-erythro-L-gluco-nononic acid

Malcolm Chandler, Mark J. Bamford, Richard Conroy et al. · Journal of the Chemical Society Perkin Transactions 1 · 1995 · 89 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Christopher R. Wellaway, Dominique Amans, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A Photoaffinity‐Based Fragment‐Screening Platform for Efficient Identification of Protein Ligands

Emma K. Grant, David J. Fallon, Michael M. Hann et al. · Angewandte Chemie International Edition · 2020 · 59 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +13

Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor

John Liddle, Francis Atkinson, Michael D. Barker et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 54 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9