Patrick C. O’Leary

RASA2 ablation in T cells boosts antigen sensitivity and long-term function

Julia Carnevale, Eric Shifrut, Nupura Kale et al. · Nature · 2022 · 223 citations · Full text

Life Sciences, Immunology, Oncology +17

A protein interaction landscape of breast cancer

Minkyu Kim, Jisoo Park, Mehdi Bouhaddou et al. · Science · 2021 · 162 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer

Patrick C. O’Leary, Marta Terrile, Małgorzata Bajor et al. · Breast Cancer Research · 2014 · 80 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents

Małgorzata Bajor, Agata O. Zych, Agnieszka Graczyk‐Jarzynka et al. · British Journal of Cancer · 2018 · 62 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo

Taha Y. Taha, Rahul K. Suryawanshi, Irene P. Chen et al. · PLoS Pathogens · 2023 · 35 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +15