Maria Emanuela Cuomo

DNA stretching induces Cas9 off-target activity

Matthew D. Newton, Ben Taylor, Rosalie P.C. Driessen et al. · Nature Structural & Molecular Biology · 2019 · 155 citations · Full text

Natural Sciences, Molecular Biology, Dna Replication +4

Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions

Nicolas Floc’h, Matthew J. Martin, Jonathan W. Riess et al. · Molecular Cancer Therapeutics · 2018 · 110 citations · Full text

A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments

Gerwin Huls, Ingmar Heijnen, Maria Emanuela Cuomo et al. · Nature Biotechnology · 1999 · 96 citations

Antitumor Activity, Human Monoclonal Antibody, Immunology +8

BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B

Matthew A. Coelho, Songyuan Li, Luna Simona Pane et al. · BMC Biology · 2018 · 95 citations · Full text

CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs

Matthew A. Coelho, Étienne De Braekeleer, Mike Firth et al. · Nature Communications · 2020 · 75 citations · Full text