Dhananjay Bakhle

Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure–Activity Relationship and Preclinical Characterization

Neelima Sinha, Navnath P. Karche, Mahip Verma et al. · Journal of Medicinal Chemistry · 2019 · 25 citations · Full text

Pharmacy, Neuroscience, Pharmacology +15

A prospective, randomized, parallel group, double blind, multicenter study to compare the efficacy, safety and immunogenicity of Lupin’s Ranibizumab with Lucentis® in patients with neovascular age-related macular degeneration

Ramandeep Singh, Rohan Chauhan, Ashish Saxena et al. · Indian Journal of Ophthalmology · 2022 · 22 citations · Full text

Medicine, Ophthalmology, Pharmacotherapy +15

A Comparative Study to Assess the Efficacy, Safety, and Immunogenicity of YLB113 and the Etanercept Reference Product for the Treatment of Patients with Rheumatoid Arthritis

Hisashi Yamanaka, Naoyuki Kamatani, Yoshiya Tanaka et al. · Rheumatology and Therapy · 2019 · 20 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13

Discovery of Potent, Selective, and State-Dependent Na_V1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure–Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides

Ramdas Vidya, Rashmi Talwar, Vijay Kanoje et al. · Journal of Medicinal Chemistry · 2020 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly(ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization

Navnath P. Karche, Mandar Bhonde, Neelima Sinha et al. · Bioorganic & Medicinal Chemistry · 2020 · 13 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16