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Discovery of isoquinolinone and naphthyridinone-based inhibitors of poly(ADP-ribose) polymerase-1 (PARP1) as anticancer agents: Structure activity relationship and preclinical characterization

Medicinal ChemistryStructure Activity RelationshipPharmaceutical ScienceNaphthyridinone-based InhibitorsBiochemistryMedicineNatural SciencesRational Drug DesignAnticancer AgentsAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery