Ling‐Ya Chiu

Oxidative stress initiates DNA damager MNNG-induced poly(ADP-ribose)polymerase-1-dependent parthanatos cell death

Ling‐Ya Chiu, Feng‐Ming Ho, Shine‐Gwo Shiah et al. · Biochemical Pharmacology · 2010 · 90 citations

Reductive Stress, Genome Instability, Dna Damage +11

mSignatureDB: a database for deciphering mutational signatures in human cancers

Po-Jung Huang, Ling‐Ya Chiu, Chi‐Ching Lee et al. · Nucleic Acids Research · 2017 · 73 citations · Full text

Engineering, Genetics, Databases +23

PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages

Ling‐Ya Chiu, Duen-Yi Huang, Wan‐Wan Lin · Cellular and Molecular Life Sciences · 2022 · 35 citations · Full text

PARP‐1 involves in UVB‐induced inflammatory response in keratinocytes and skin injury via regulation of ROS‐dependent EGFR transactivation and p38 signaling

Ling‐Ya Chiu, Nan‐Lin Wu, Chi‐Feng Hung et al. · The FASEB Journal · 2021 · 34 citations · Full text

Parp Inhibitor Olaparib, P38 Activation, Immunology +16

Critical roles of irradiance in the regulation of UVB-induced inflammasome activation and skin inflammation in human skin keratinocytes

Te-An Lee, Yi‐Ting Huang, Pa‐Fan Hsiao et al. · Journal of Photochemistry and Photobiology B Biology · 2021 · 24 citations

Inflammation, Skin Inflammation, Cutaneous Biology +9