Stuart T. Caldwell

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.7K citations · Full text

Inflammation, Reductive Stress, Anti-inflammatory +10

Highly stable tetrathiafulvalene radical dimers in [3]catenanes

Jason M. Spruell, Ali Coşkun, Douglas C. Friedman et al. · Nature Chemistry · 2010 · 181 citations

Chemistry, Heterocycle Chemistry

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

Jack L. Martin, Ana S.H. Costa, Anja V. Gruszczyk et al. · Nature Metabolism · 2019 · 155 citations

Transplantation, Hematology, Sepsis +3

Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation

Daniel J. Fazakerley, Annabel Y. Minard, James R. Krycer et al. · Journal of Biological Chemistry · 2018 · 154 citations · Full text

Selective Uncoupling of Individual Mitochondria within a Cell Using a Mitochondria-Targeted Photoactivated Protonophore

Susan Chalmers, Stuart T. Caldwell, Caroline Quin et al. · Journal of the American Chemical Society · 2011 · 119 citations · Full text

Photobiology, Molecular Biology, Individual Mitochondria +18