Jason H. Chaplin

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[<i>b</i>]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

Bernard L. Flynn, Gurmit S. Gill, Damian Grobelny et al. · Journal of Medicinal Chemistry · 2011 · 139 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Complexes of Trypanosoma cruzi Sterol 14α-Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease

Tatiana Y. Hargrove, Z. Wawrzak, Paul W. Alexander et al. · Journal of Biological Chemistry · 2013 · 78 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +17

Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease

Martine Keenan, Michael J. Abbott, Paul W. Alexander et al. · Journal of Medicinal Chemistry · 2012 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A multi-component coupling approach to benzo[b]furans and indoles

Jason H. Chaplin, Bernard L. Flynn · Chemical Communications · 2001 · 58 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Oxazolidinone-Promoted, Torquoselective Nazarov Cyclizations

Daniel J. Kerr, Michael Miletic, Jason H. Chaplin et al. · Organic Letters · 2012 · 55 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6