Dechang Zhang

Carboxyamidotriazole inhibits oxidative phosphorylation in cancer cells and exerts synergistic anti-cancer effect with glycolysis inhibition

Rui Jü, Lei Guo, Juan Li et al. · Cancer Letters · 2015 · 51 citations

Oncology, Medicine, Tumor Targeting +7

Therapeutic efficacy of carboxyamidotriazole on 2,4,6-trinitrobenzene sulfonic acid-induced colitis model is associated with the inhibition of NLRP3 inflammasome and NF-κB activation

Xiao-wan Du, Wei Chen, Yufeng Wang et al. · International Immunopharmacology · 2017 · 42 citations

Inflammation, Chronic Inflammatory Diseases, Anti-inflammatory +13

Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model

Ruifang Mi, Jianhui Ma, Dechang Zhang et al. · Journal of genetics and genomics/Journal of Genetics and Genomics · 2009 · 36 citations

Signal Transduction, Cell Regulation, Novel Therapy +12

Carboxyamidotriazole combined with IDO1-Kyn-AhR pathway inhibitors profoundly enhances cancer immunotherapy

Jing Shi, Chen Chen, Rui Jü et al. · Journal for ImmunoTherapy of Cancer · 2019 · 35 citations · Full text

Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

Jing Shi, Rui Jü, Hongting Gao et al. · Acta Pharmaceutica Sinica B · 2021 · 34 citations · Full text