Lei Guo

Carboxyamidotriazole inhibits oxidative phosphorylation in cancer cells and exerts synergistic anti-cancer effect with glycolysis inhibition

Rui Jü, Lei Guo, Juan Li et al. · Cancer Letters · 2015 · 51 citations

Oncology, Medicine, Tumor Targeting +7

Therapeutic efficacy of carboxyamidotriazole on 2,4,6-trinitrobenzene sulfonic acid-induced colitis model is associated with the inhibition of NLRP3 inflammasome and NF-κB activation

Xiao-wan Du, Wei Chen, Yufeng Wang et al. · International Immunopharmacology · 2017 · 42 citations

Inflammation, Chronic Inflammatory Diseases, Anti-inflammatory +13

Targeting glutamine utilization to block metabolic adaptation of tumor cells under the stress of carboxyamidotriazole-induced nutrients unavailability

Jing Shi, Rui Jü, Hongting Gao et al. · Acta Pharmaceutica Sinica B · 2021 · 34 citations · Full text

Regulator of G protein signaling proteins differentially modulate signaling of μ and δ opioid receptors

Zhihua Xie, Zhisong Li, Lei Guo et al. · European Journal of Pharmacology · 2007 · 29 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +13

Carboxyamidotriazole Synergizes with Sorafenib to Combat Non–Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis

Chen Chen, Rui Jü, Jing Shi et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 22 citations · Full text