Robert A. Langish

Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition

Yurong Lai, Sandhya Mandlekar, Hong Shen et al. · Journal of Pharmacology and Experimental Therapeutics · 2016 · 169 citations

Medicine, Pharmacokinetics, Pharmacology +14

Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects

Hong Shen, Weiqi Chen, Dieter M. Drexler et al. · Drug Metabolism and Disposition · 2017 · 83 citations

Medicine, Pharmacokinetics, Pharmacology +14

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Aiying Wang, Charles R. Dorso, Lisa M. Kopcho et al. · BMC Pharmacology · 2012 · 60 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Application of ion trap technology to liquid chromatography/mass spectrometry quantitation of large peptides

Petia Shipkova, Dieter M. Drexler, Robert A. Langish et al. · Rapid Communications in Mass Spectrometry · 2008 · 43 citations

Natural Sciences, Biochemistry, Chemistry +15

An Automated High Throughput Liquid Chromatography–Mass Spectrometry Process to Assess the Metabolic Stability of Drug Candidates

Dieter M. Drexler, James V. Belcastro, Kenneth E.J. Dickinson et al. · Assay and Drug Development Technologies · 2007 · 37 citations

Pharmacy, Biochemistry, Pharmacology +17