Colin W. Garvie

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler et al. · Nature Cancer · 2020 · 883 citations · Full text

Medicine, Oncology, Pharmacology +13

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Bradford Graves, Thelma Thompson, Mingxuan Xia et al. · Proceedings of the National Academy of Sciences · 2012 · 227 citations · Full text

Medicine, Cancer Biology, Oncology +14

Structural Studies of Ets-1/Pax5 Complex Formation on DNA

Colin W. Garvie, James Hagman, Cynthia Wolberger · Molecular Cell · 2001 · 199 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

Colin W. Garvie, Xiaoyun Wu, Malvina Papanastasiou et al. · Nature Communications · 2021 · 90 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships

Colin W. Garvie, Miles A. Pufall, Barbara J. Graves et al. · Journal of Biological Chemistry · 2002 · 87 citations · Full text

Life Sciences, Biology, Molecular Biology +13