F.J. Sorrell

Family-wide Structural Analysis of Human Numb-Associated Protein Kinases

F.J. Sorrell, M. Szklarz, Kamal R. Abdul Azeez et al. · Structure · 2016 · 149 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +13

Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases

Daniel M. Pinkas, C. Sanvitale, Joshua C. Bufton et al. · Biochemical Journal · 2017 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman et al. · Cell Reports · 2019 · 96 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structural and biochemical characterization of the KLHL3–WNK kinase interaction important in blood pressure regulation

Frances‐Rose Schumacher, F.J. Sorrell, Dario R. Alessi et al. · Biochemical Journal · 2014 · 78 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Synthesis and Structure–Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3-<i>b</i>]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity

Sven Verdonck, Szu‐Yuan Pu, F.J. Sorrell et al. · Journal of Medicinal Chemistry · 2019 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16