Antonio Mete

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

Elsa D. Garcin, A.S. Arvai, R.J. Rosenfeld et al. · Nature Chemical Biology · 2008 · 264 citations · Full text

Anchored Plasticity, Engineering, Biochemistry +11

Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A₂ Based on a 1,3-Disubstituted Propan-2-one Skeleton

Stephen Connolly, Colin Bennion, Sarah Botterell et al. · Journal of Medicinal Chemistry · 2002 · 84 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Enzyme Active Site +15

Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate

Mark Furber, A.K. Tiden, Philip Gardiner et al. · Journal of Medicinal Chemistry · 2014 · 54 citations · Full text

Drug Target, Cathepsin C Inhibitors, Lead Identification +17

Palladium catalysed amination of electron deficient halothiophenes

Tim Luker, Haydn G. Beaton, Matthew Whiting et al. · Tetrahedron Letters · 2000 · 52 citations

Engineering, Organic Chemistry, Electron Deficient Halothiophenes +4

Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists

Nicholas D. Kindon, Glen K. Andrews, Andrew Baxter et al. · ACS Medicinal Chemistry Letters · 2017 · 29 citations · Full text