Javier Murciano‐Calles

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation

Andrew R. Buller, Sabine Brinkmann‐Chen, David K. Romney et al. · Proceedings of the National Academy of Sciences · 2015 · 169 citations · Full text

Protein Function, Signal Transduction, Tryptophan Analogs +13

Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues

David K. Romney, Javier Murciano‐Calles, Jöri E. Wehrmüller et al. · Journal of the American Chemical Society · 2017 · 132 citations · Full text

Engineering, Trp Analogues, Tryptophan Analogues +17

A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation

Javier Murciano‐Calles, David K. Romney, Sabine Brinkmann‐Chen et al. · Angewandte Chemie International Edition · 2016 · 78 citations

Tryptophan Synthase, Biochemistry, Tryptophan Synthase β‐Subunit +12

Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes

Victoria Sánchez-Martín, María del Carmen Plaza‐Calonge, Ana Soriano‐Lerma et al. · Cancers · 2022 · 37 citations · Full text

Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity

Andrew R. Buller, P. van Roye, Javier Murciano‐Calles et al. · Biochemistry · 2016 · 29 citations

Biosynthesis, Tryptophan Synthase, Biochemistry +13