Sabine Brinkmann‐Chen

Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme

Christopher K. Prier, Ruijie K. Zhang, Andrew R. Buller et al. · Nature Chemistry · 2017 · 377 citations · Full text

Engineering, Organic Chemistry, Catalysis +6

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation

Andrew R. Buller, Sabine Brinkmann‐Chen, David K. Romney et al. · Proceedings of the National Academy of Sciences · 2015 · 169 citations · Full text

Protein Function, Signal Transduction, Tryptophan Analogs +13

A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases

Jackson K. B. Cahn, Caroline A. Werlang, Armin Baumschlager et al. · ACS Synthetic Biology · 2016 · 148 citations · Full text

Bioorganic Chemistry, Engineering, Aldo-keto Reductase +20

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH

Sabine Brinkmann‐Chen, Tilman Flock, Jackson K. B. Cahn et al. · Proceedings of the National Academy of Sciences · 2013 · 117 citations · Full text

Bioorganic Chemistry, Aldo-keto Reductase, Molecular Biology +17

Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase

Michael Herger, P. van Roye, David K. Romney et al. · Journal of the American Chemical Society · 2016 · 96 citations · Full text