Concepedia

Shehab Ismail

SI

34

Publications

3.1K

Citations

23

H-Index

1985

Active since

Affiliations

Cancer Research UK Scotland Institute(Current)

University of Glasgow

Max Planck Institute of Molecular Physiology

TU Dortmund University

Max Planck Society

Shehab Ismail is an author at Cancer Research UK Scotland Institute specializing in medicine, signal transduction, and natural sciences.

Top concepts

MedicineNatural SciencesSignal TransductionMolecular BiologyCell BiologyCell SignalingCellular BiochemistryBiochemistryCell PhysiologySystems Biology

Publications per year

1985–2025

34

Publications

34

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

Gunther Zimmermann, Bjoern Papke, Shehab Ismail et al. · Nature · 2013 · 591 citations

Inhibitory Activity, Signal Transduction, Molecular Regulation +12

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

Anchal Chandra, Hernán E. Grecco, Venkat Pisupati et al. · Nature Cell Biology · 2011 · 320 citations

Protein Function, Signal Transduction, Protein Assembly +12

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Shehab Ismail, Yong‐Xiang Chen, Alexandra Rusinova et al. · Nature Chemical Biology · 2011 · 255 citations

Gdi-like Transport System, Arl3-gtp Regulate, Natural Sciences +3

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

Steven Reid, Emily Kay, Lisa J. Neilson et al. · The EMBO Journal · 2017 · 195 citations · Full text

Identification of pyrazolopyridazinones as PDEδ inhibitors

Bjoern Papke, Sandip Murarka, Holger A. Vogel et al. · Nature Communications · 2016 · 160 citations · Full text

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