Lesley A. Houghton

Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin.

Chander Shekhar, Monaghan Pj, Jane Morris et al. · IRIS Research product catalog (Sapienza University of Rome) · 2013 · 2.7K citations

Medicine, Pharmacology, Gastroenterology +16

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

Dipesh H. Vasant, Peter Paine, Christopher J. Black et al. · Gut · 2021 · 504 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13

Altered 5-Hydroxytryptamine Signaling in Patients With Constipation- and Diarrhea-Predominant Irritable Bowel Syndrome

Wendy Atkinson, Stephen Lockhart, Peter J. Whorwell et al. · Gastroenterology · 2006 · 354 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13

Clinical trial: the effects of a fermented milk product containing <i>Bifidobacterium lactis</i> DN‐173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation

A. Agrawal, Lesley A. Houghton, J.A. Morris et al. · Alimentary Pharmacology & Therapeutics · 2008 · 315 citations

Agriculture, Nutrition, Nutritional Sciences +17

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

Chris Eijsbouts, Tenghao Zheng, Nicholas A. Kennedy et al. · Nature Genetics · 2021 · 282 citations · Full text

Life Sciences, Genetics, Psychiatry +16