Sean Nygaard

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model

Leszek Lisowski, Allison Dane, Kirk Chu et al. · Nature · 2013 · 452 citations

Life Sciences, Genetics, Molecular Medicine +11

Long-Term Potentiation-Dependent Spine Enlargement Requires Synaptic Ca²⁺-Permeable AMPA Receptors Recruited by CaM-Kinase I

Dale A. Fortin, Monika A. Davare, Taasin Srivastava et al. · Journal of Neuroscience · 2010 · 200 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

Nicole K. Paulk, Katja Pekrun, Erhua Zhu et al. · Molecular Therapy · 2017 · 164 citations · Full text

Life Sciences, Biomolecular Engineering, Molecular Biology +11

Brain-Derived Neurotrophic Factor Activation of CaM-Kinase Kinase via Transient Receptor Potential Canonical Channels Induces the Translation and Synaptic Incorporation of GluA1-Containing Calcium-Permeable AMPA Receptors

Dale A. Fortin, Trilochan Srivastava, D. Dwarakanath et al. · Journal of Neuroscience · 2012 · 119 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors

Katja Pekrun, Gustavo de Alencastro, Qing-Jun Luo et al. · JCI Insight · 2019 · 102 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14