Jenni Cryan

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Alina Mares, Afjal H. Miah, Ian E. Smith et al. · Communications Biology · 2020 · 221 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

Chun‐wa Chung, Han Dai, Esther Fernández et al. · ACS Chemical Biology · 2020 · 88 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +15

Selective CDK6 degradation mediated by cereblon, VHL, and novel IAP-recruiting PROTACs

Niall A. Anderson, Jenni Cryan, Adil Ahmed et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 67 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Internalization of the chemokine receptor CCR4 can be evoked by orthosteric and allosteric receptor antagonists

Laura Ajram, Malcolm Begg, Robert J. Slack et al. · European Journal of Pharmacology · 2014 · 53 citations · Full text

Medicine, Immunology, Pharmacology +17

A Potent and Selective Kallikrein-5 Inhibitor Delivers High Pharmacological Activity in Skin from Patients with Netherton Syndrome

John Liddle, Véronique Bénéton, Matthew A. Benson et al. · Journal of Investigative Dermatology · 2021 · 32 citations

Medicine, Dermatology, Pharmacology +2