J Hearst

Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long‐wavelength ultraviolet light

L. Lin, David N. Cook, Gary Wiesehahn et al. · Transfusion · 1997 · 342 citations

Life Sciences, Biology, Microbiology +17

Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity

Dirk G. Brockstedt, Keith S. Bahjat, Martin Giedlin et al. · Nature Medicine · 2005 · 135 citations

Life Sciences, Immunology, Microbiology +17

Solution Structures of Psoralen Monoadducted and Cross-Linked DNA Oligomers by NMR Spectroscopy and Restrained Molecular Dynamics

H. Peter Spielmann, Tammy J. Dwyer, J Hearst et al. · Biochemistry · 1995 · 75 citations

Life Sciences, Biochemistry, Molecular Biology +14

DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair.

H. Peter Spielmann, Tammy J. Dwyer, Srin Sastry et al. · Proceedings of the National Academy of Sciences · 1995 · 59 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Evidence for structural deformation of the DNA helix by a psoralen diadduct but not by a monoadduct

Yun‐Bo Shi, Jack D. Griffith, Hannes Gamper et al. · Nucleic Acids Research · 1988 · 21 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13