Chandra Vargeese

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

Jennifer A. Lockridge, Lucinda Shaw, Karin S. Blanchard et al. · Nature Biotechnology · 2005 · 1.2K citations

Medicinal Chemistry, Viral Hepatitis, Immunology +9

Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides

Naoki Iwamoto, David C. Butler, Nenad Svrzikapa et al. · Nature Biotechnology · 2017 · 358 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +7

Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1

Jikui Shen, Rebecca Samul, R L Silva et al. · Gene Therapy · 2005 · 305 citations

Ocular Disease, Angiogenesis, Ophthalmology +6

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication†

Karin S. Blanchard, Lucinda Shaw, Kristi Jensen et al. · Hepatology · 2005 · 290 citations · Full text

Novel Approach to Specific Growth Factor Inhibition in Vivo

Jürgen Floege, Tammo Ostendorf, Ulf Janssen et al. · American Journal Of Pathology · 1999 · 232 citations · Full text

Growth Hormone, Medicine, Novel Approach +5